Human Male Sexuality: Endocrine Disruption and Male Reproductive Wellness

Human Male Sexuality: Endocrine Disruption and Male Reproductive Wellness

Human Male Sexuality: Endocrine Disruption and Male Reproductive Wellness

9.1 Introduction

Male sexuality is decided genetically during the time of fertilization by the existence of the Y chromosome into the spermatozoan since it fuses aided by the X-chromosome-containing ovum, and also the sex-determining area associated with Y chromosome (SRY) then drives the bipotential gonad associated with embryo to be a testis through hormone-independent mechanisms 1,2. Nevertheless, after the very early testis is formed, growth of the total male phenotype, including further testicular development (masculinization), becomes totally determined by a complex system of hormonal signals, especially hormones secreted through the testes 2. People who lack any gonads are phenotypically female 1 and intervention that is endocrine needed to change the standard feminine phenotype to be male 2. This will make both development and upkeep of masculinization at risk of endocrine-disrupting impacts after all developmental phases from very early embryo to adulthood; in specific, interruption of very very early embryonic developmental processes could have consequences for male reproductive health in adult life 2. This chapter will deal with the results of endocrine interruption for growth of the urogenital tract and for sperm production. It’s going to talk about the cap cap ability of endocrine-disrupting chemicals (EDCs) to bring about improper breast development (gynecomastia), alterations to puberty, and hyperplasia in prostatic muscle ( Figure 9.1 ). Czytaj więcej about Human Male Sexuality: Endocrine Disruption and Male Reproductive Wellness